20 Best Southwest American Restaurants In Winston-Salem

A photo of Jeffrey Adams on Fourth restaurant

1. Jeffrey Adams on Fourth

4.7

Exceptional(1988)

Price: Expensive

• Mexican • Winston-Salem

Booked 36 times today

Jeffrey Adams on Fourth in Winston-Salem is a beacon of exceptional Steakhouse cuisine, celebrated for its impeccable quality and authenticity. "The filet was perfectly done," raves one diner, highlighting the mastery in steak preparation that sets this restaurant apart. Guests consistently praise the "fantastic selection" of menu offerings, from hearty steaks to delectable seafood risottos, ensuring a delightful experience for all palates. The wood-fired grill imparts a distinctive smoky flavor, enhancing the succulent taste of each steak. With an inviting atmosphere and attentive service, Jeffrey Adams on Fourth is poised to impress, making it a must-visit for steak enthusiasts.

2. Six Hundred°

4.7

Exceptional(678)

Price: Expensive

• Mexican • Winston-Salem

Booked 21 times today

At Six Hundred°, located in the historic Bailey Powerplant in Winston-Salem, the Prime Rib is nothing short of extraordinary. Known for its chef-driven menu, this upscale dining establishment offers a Prime Rib experience that is both authentic and sublime. The culinary team ensures that each cut is “cooked perfectly,” achieving the ideal temperature every time, as noted by satisfied diners. The ambiance enhances the dining experience, with patrons relishing the “phenomenal” service and the opportunity to watch chefs at work. With glowing reviews applauding its “outstanding” food and service, Six Hundred° is the ultimate destination for Prime Rib enthusiasts.

A photo of Spotted Cow Steakhouse restaurant

3. Spotted Cow Steakhouse

4.6

Exceptional(300)

Price: Moderate

• Mexican • Winston-Salem

Booked 29 times today

At Spotted Cow Steakhouse in Winston-Salem, the steak experience is nothing short of exceptional. This cozy and inviting boutique steakhouse is renowned for its top-quality cuts, with the filet mignon and ribeye taking center stage. Diners rave about the "steak cooked to perfection," exuding rich, buttery flavors that elevate their dining experience. The staff's genuine hospitality and attentiveness enhance the atmosphere, making every meal memorable. Guests frequently highlight the "perfectly cooked" steaks and generous portions, ensuring a satisfying and gratifying visit. If you're seeking authentic steak cuisine with a warm, family-friendly vibe, Spotted Cow Steakhouse is a must-visit destination.

A photo of 6th and Vine Restaurant and Wine Bar restaurant

4. 6th and Vine Restaurant and Wine Bar

4.5

Awesome(60)

Price: Expensive

• Mexican • Winston-Salem

Booked 15 times today

Located in the vibrant Arts District of downtown Winston-Salem, 6th and Vine Restaurant and Wine Bar is a beacon of authentic Bistro cuisine. With a menu crafted by Executive Chef Michael Spencer, guests are treated to a "fantastic farm to fork menu" where fresh, locally-sourced ingredients shine. The restaurant's award-winning wine list complements the delectable small plates, such as the highly praised burrata and charcuterie board, which are perfect for sharing. Diners rave about the "inventive, fabulously flavorful" dishes, and the charming patio provides a delightful backdrop for enjoying this culinary gem. Whether indulging in brunch or dinner, 6th and Vine promises an unforgettable dining experience.

5. Butcher & Bull

3.2

Good(278)

Price: Moderate

• Mexican • Winston-Salem

Booked 5 times today

Butcher & Bull in downtown Winston-Salem is a shining star of authentic American cuisine, offering a contemporary twist on the classic steakhouse experience. Executive Chef Timothy Gallione crafts exceptional dishes, with patrons raving about the "incredible" flavors and perfectly cooked meats like the 12oz Bison NY Strip. Guests commend the "amazing" Thanksgiving and Easter buffets, highlighting the freshness and variety of the offerings. The atmosphere, described as "excellent," complements the attentive service, with staff ensuring every dining experience is memorable. Whether enjoying a quick drink or a full meal, Butcher & Bull promises a delightful American dining adventure.

6. Mozelle's

4.9

Exceptional(2980)

Price: Moderate

• Mexican • Winston-Salem

Booked 34 times today

Mozelle’s Fresh Southern Bistro in Winston-Salem offers an authentic American dining experience with a delightful Southern twist. Known for its “superb Southern cooking,” Mozelle's uses the "finest and freshest ingredients" to craft dishes that leave a lasting impression. Diners rave about the fried chicken, shrimp and grits, and the "divine tomato pie," which are all standout favorites. The cozy, lively atmosphere and attentive service enhance the dining experience, providing a welcoming vibe that draws patrons back time and again. With its "exceptional food and service," Mozelle’s is truly "a gem" in the heart of Winston-Salem, perfect for both everyday dining and special occasions.

A photo of Sage & Salt Bistro restaurant

7. Sage & Salt Bistro

4.7

Exceptional(516)

Price: Expensive

• Mexican • Winston-Salem

Booked 75 times today

Sage & Salt Bistro in Winston-Salem is a must-visit for aficionados of Contemporary American cuisine. Guests rave about the "fantastic food" and "outstanding meal and service," highlighting the restaurant's ability to blend traditional flavors with modern flair. Diners have been particularly impressed by the expertly cooked steaks and the creative twists on classic dishes, like the "best risottos" paired with scallops. The attentive staff and warm ambiance, often complemented by live jazz, create a dining experience that feels both special and inviting. Whether celebrating an anniversary or simply enjoying a night out, Sage & Salt promises a memorable culinary journey.

8. Betty on Burke

4.8

Exceptional(155)

Price: Moderate

• Mexican • Winston-Salem

Booked 39 times today

Nestled in the heart of downtown Winston-Salem, Betty on Burke is a fresh and exciting addition to the city’s thriving dining scene. From the team behind Mozelle’s, a beloved local favorite, Betty on Burke brings its own unique flair, offering an inviting atmosphere where exceptional food and hospitality take center stage.Step inside and be transported by a stylish, bamboo-wrapped space that feels like a hidden gem just off bustling Burke Street. Our menu celebrates bold, approachable flavors with an elevated twist, designed to delight locals and visitors alike. Whether you’re indulging in a leisurely dinner or sharing small plates with friends, every dish is crafted to create memorable moments.As a locally owned gem with deep ties to the community, Betty on Burke is proud to carry on the legacy of excellence that Mozelle’s has established. Join us for an unforgettable dining experience that perfectly balances fun, flavor, and charm—right in the heart of Winston-Salem.

A photo of Rooster's A Noble Grille restaurant

9. Rooster's A Noble Grille

4.7

Exceptional(2207)

Price: Expensive

• Mexican • Winston-Salem

Booked 40 times today

Rooster's A Noble Grille in Winston-Salem proudly showcases the best of American cuisine with an unwavering commitment to quality and authenticity. Founded by North Carolina chef Jim Noble, the restaurant thrives on the belief that "simple food is harder to execute," ensuring each dish is a masterpiece crafted from locally sourced ingredients. Diners rave about the "outstanding service" and "exceptional food," with favorites like the spit-roasted chicken cooked over an open fire. The atmosphere is both welcoming and refined, making it perfect for any occasion. With consistently rave reviews, Rooster's promises an unforgettable dining experience steeped in authentic American flavors.

A photo of Bernardin's Restaurant at the Zevely House restaurant

10. Bernardin's Restaurant at the Zevely House

4.7

Exceptional(1838)

Price: Moderate

• Mexican • Winston-Salem

Booked 11 times today

Bernardin's Restaurant at the Zevely House in Winston-Salem is a shining beacon of Contemporary American cuisine, celebrated for its “rich and tasty” flavors and impeccable execution. Nestled in a charming historic house, the atmosphere is both cozy and elegant, perfect for a special occasion or a delightful date night. The menu is diverse, offering unique dishes like the highly-praised Lobster Lobster and Filet Mignon, each cooked to perfection. Guests rave about the attentive and friendly service, with standout mentions of staff members like Josh and Katie, ensuring a memorable dining experience. Discover why Bernardin’s is a cherished gem in Winston-Salem.

Best Southwest American Restaurants in Winston-Salem

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20 restaurants available nearby

1. Jeffrey Adams on Fourth

2. Six Hundred°

3. Spotted Cow Steakhouse

4. 6th and Vine Restaurant and Wine Bar

5. Butcher & Bull

6. Mozelle's

7. Sage & Salt Bistro

8. Betty on Burke

9. Rooster's A Noble Grille

10. Bernardin's Restaurant at the Zevely House

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